Invention Grant
- Patent Title: Inhibitors of histone deacetylase
- Patent Title (中): 组蛋白脱乙酰酶抑制剂
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Application No.: US12043450Application Date: 2008-03-06
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Publication No.: US08030344B2Publication Date: 2011-10-04
- Inventor: Sylvie Frechette , Lubo Isakovic , Isabelle Paquin , Simon Roy , Oscar Moradei , Arkadii Vaisburg
- Applicant: Sylvie Frechette , Lubo Isakovic , Isabelle Paquin , Simon Roy , Oscar Moradei , Arkadii Vaisburg
- Applicant Address: CA Montreal
- Assignee: MethylGene Inc.
- Current Assignee: MethylGene Inc.
- Current Assignee Address: CA Montreal
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C07D207/00
Abstract:
The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. One aspect of the invention provides compounds of formula (1): in which T, A and X are as described herein.
Public/Granted literature
- US20080227826A1 Inhibitors of Histone Deacetylase Public/Granted day:2008-09-18
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