Invention Grant
US08030493B2 Monovalent and divalent salts of N-(5-hydroxynicotinoil) -L-glutamic acid exhibiting psychotropic (antidepressant and anxiolytic), neuroprotective, geroprotective and cerebroprotective action
有权
显示精神药物(抗抑郁药和抗焦虑药)的N-(5-羟基烟酰基)-L-谷氨酸的单价和二价盐,神经保护,保护作用和保护脑保护作用
- Patent Title: Monovalent and divalent salts of N-(5-hydroxynicotinoil) -L-glutamic acid exhibiting psychotropic (antidepressant and anxiolytic), neuroprotective, geroprotective and cerebroprotective action
- Patent Title (中): 显示精神药物(抗抑郁药和抗焦虑药)的N-(5-羟基烟酰基)-L-谷氨酸的单价和二价盐,神经保护,保护作用和保护脑保护作用
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Application No.: US12309543Application Date: 2007-06-06
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Publication No.: US08030493B2Publication Date: 2011-10-04
- Inventor: Pavel Vasilyevich Yakimuk , Sergey Vitalyevich Stovbun , Alexandr Anatolyevich Litvin
- Applicant: Pavel Vasilyevich Yakimuk , Sergey Vitalyevich Stovbun , Alexandr Anatolyevich Litvin
- Applicant Address: RU Tulskaya obl.
- Assignee: Obschestvo S Ogranichennoy Otvetstvennostyu “Natsionalnaya Isseldovatelskaya Kompaniya”
- Current Assignee: Obschestvo S Ogranichennoy Otvetstvennostyu “Natsionalnaya Isseldovatelskaya Kompaniya”
- Current Assignee Address: RU Tulskaya obl.
- Agency: Collard & Roe, P.C.
- Priority: RU2006127564 20060731
- International Application: PCT/RU2007/000304 WO 20070606
- International Announcement: WO2008/018815 WO 20080214
- Main IPC: C07D213/04
- IPC: C07D213/04

Abstract:
The invention relates to medicine, in particular to mono- and divalent salts of N-(5-hydroxynicotinoil)-L-glutaminic acid exhibiting psychotropic antidepressant, anxiolytic, heroprotective, neuroprotective, antihypoxia cerebroprotective and nootropic action. The novel compounds differ from the known preparations, including the closest prior art in the form of a N-(5-hydroxynicotinoil)-L-glutaminic acid base (nooglucotyl), in that they produce psychotropic effects, namely antidepressant, anxiolytic, neuroprotective and heroprotective actions, in such a way that lesion focuses caused by apoplectic attacks are reduced and age-specific neurological deficiencies and intellectual and physical work capacities are improved.
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