Invention Grant
US08030496B2 Intermediate compound for synthesis of viridiofungin a derivative
失效
用于合成维生素E衍生物的中间体化合物
- Patent Title: Intermediate compound for synthesis of viridiofungin a derivative
- Patent Title (中): 用于合成维生素E衍生物的中间体化合物
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Application No.: US12656579Application Date: 2010-02-04
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Publication No.: US08030496B2Publication Date: 2011-10-04
- Inventor: Tatsuya Kato , Nobuaki Kimura , Akemi Mizutani , Toshihiko Makino , Kenichi Kawasaki , Hiroshi Fukuda , Susumu Komiyama , Takuo Tsukuda
- Applicant: Tatsuya Kato , Nobuaki Kimura , Akemi Mizutani , Toshihiko Makino , Kenichi Kawasaki , Hiroshi Fukuda , Susumu Komiyama , Takuo Tsukuda
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaki Kabushiki Kaisha
- Current Assignee: Chugai Seiyaki Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2005-041153 20050217
- Main IPC: C07D413/00
- IPC: C07D413/00
Abstract:
A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided.A compound represented by the formula (1-8): wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R′, etc.; and n represents an integer of 0 to 10.
Public/Granted literature
- US20100152456A1 Intermediate compound for synthesis of viridiofungin a derivative Public/Granted day:2010-06-17
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