Invention Grant
US08030506B2 Tumor selective and biodegradable cyclotriphosphazene-platinum(II) conjugate anticancer agent, and preparation method thereof
失效
肿瘤选择性和生物降解性环三磷腈 - 铂（II）缀合物抗癌剂及其制备方法
- Patent Title: Tumor selective and biodegradable cyclotriphosphazene-platinum(II) conjugate anticancer agent, and preparation method thereof
- Patent Title (中): 肿瘤选择性和生物降解性环三磷腈 - 铂（II）缀合物抗癌剂及其制备方法
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Application No.: US12595943Application Date: 2008-04-11
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Publication No.: US08030506B2Publication Date: 2011-10-04
- Inventor: Youn-Soo Sohn , Ji-Young Yu , Yong-Joo Jun
- Applicant: Youn-Soo Sohn , Ji-Young Yu , Yong-Joo Jun
- Applicant Address: KR Seoul
- Assignee: Nanohybrid Co., Ltd
- Current Assignee: Nanohybrid Co., Ltd
- Current Assignee Address: KR Seoul
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Kongsik Kim
- Priority: KR10-2007-0038055 20070418
- International Application: PCT/KR2008/002068 WO 20080411
- International Announcement: WO2008/130121 WO 20081030
- Main IPC: C07F15/00
- IPC: C07F15/00 ; A61K31/28
Abstract:
Disclosed are a novel cyclotriphosphazene-platinum(II) complex conjugate anticancer agent, showing high selectivity to tumor tissues due to the enhanced permeability and retention effect in tumor tissues and a preparation method thereof.
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