Invention Grant
US08030511B2 Method for the manufacture of therapeutic compounds and compositions, compounds and compositions produced therewith, and their use
有权
用于制备治疗化合物和组合物，由其制备的化合物和组合物的方法及其用途
- Patent Title: Method for the manufacture of therapeutic compounds and compositions, compounds and compositions produced therewith, and their use
- Patent Title (中): 用于制备治疗化合物和组合物，由其制备的化合物和组合物的方法及其用途
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Application No.: US12282878Application Date: 2007-03-14
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Publication No.: US08030511B2Publication Date: 2011-10-04
- Inventor: Lars E. Gustafsson , Dag Linnarsson , Kristofer Nilsson
- Applicant: Lars E. Gustafsson , Dag Linnarsson , Kristofer Nilsson
- Agency: Morrison & Foerster LLP
- Priority: SE0600566 20060314
- International Application: PCT/SE2007/050152 WO 20070314
- International Announcement: WO2007/106034 WO 20070920
- Main IPC: C07C203/04
- IPC: C07C203/04
Abstract:
Organic nitrites can be produced from a compound which is a mono/polyhydric alcohol or an aldehyde- or ketone-derivate thereof after de-aeration of the same, using NO gas, and stored in an environment saturated with gaseous NO. Organic nitrites produced according to the invention exhibit less impurities and improved storage stability compared to conventionally produced nitrites. The organic nitrites of the invention can easily be formulated into pharmaceutical compositions and have utility for the treatment of various conditions.
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