A method of imaging a breast comprising (i) having a patient lie prone on a computer-controlled couch, which comprises a channel or left and right openings, and position the left or right breast of the patient in the channel or the left or right opening, respectively, and (ii) repeatedly imaging the breast using a scanning x-ray source while moving the couch down and up, such that the breast moves down and up in the field between the source of radiation and the detector, which method can further comprise constructing a three-dimensional image of the breast in its natural shape and analyzing the three-dimensional image of the breast; and a system for use in such a method.