Invention Grant
- Patent Title: Method for identifying motifs and/or combinations of motifs having a boolean state of predetermined mutation in a set of sequences and its application
- Patent Title (中): 用于鉴定在一组序列中具有预定突变的布尔状态的基序和/或组合的方法及其应用
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Application No.: US12708194Application Date: 2010-02-18
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Publication No.: US08032309B2Publication Date: 2011-10-04
- Inventor: Anne Vanet , Michaela Muller-Trutwin , Thomas Valère
- Applicant: Anne Vanet , Michaela Muller-Trutwin , Thomas Valère
- Applicant Address: FR
- Assignee: Centre National de la Recherche Scientifique - CNRS
- Current Assignee: Centre National de la Recherche Scientifique - CNRS
- Current Assignee Address: FR
- Agency: DLA Piper LLP (US)
- Priority: FR0107808 20010614
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
A method for identifying a motif or a combination of motifs having a Boolean state of predetermined mutations in a set of sequences including a) aligning a set of sequences of ordered motifs represented by a single-character code, b) comparing a reference sequence with the set of sequences aligned in step (a), c) identifying motifs not having mutated simultaneously or motifs having mutated simultaneously at least once on at least one sequence of the set and not having mutated on another sequence of the set.
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