Provided are a content-based searching method and system for multimedia objects using a high-dimensional feature vector data based on a 2-level signature. The method for searching the high-dimensional data using a signature file includes calculating a first-level query signature and a second-level query signature by using the query feature vector, performing a first filtering operation to obtain a primary candidate cell group by searching a second-level signature file, and performing a secondary filtering operation to obtain a secondary candidate cell group having a high similarity in a primary candidate cell group. Accordingly, the high-dimensional data searching method and system can process a query quickly and accurately and can increase the searching accuracy by using an enhanced signature of the query feature vector.