A spatio-temporal learning node is a type of HTM node which learns both spatial and temporal groups of sensed input patterns over time. Spatio-temporal learning nodes comprise spatial poolers which are used to determine spatial groups in a set of sensed input patterns. The spatio-temporal learning nodes further comprise temporal poolers which are used to determine groups of sensed input patterns that temporally co-occur. A spatio-temporal learning network is a hierarchical network including a plurality of spatio-temporal learning nodes.