In accordance with the present technique, a system and method for configuring pins of an input/output (I/O) card in a host system are provided. The method includes reading configuration information from a card field replaceable unit memory and reading system configuration information from a system field replaceable unit memory. Additionally, the method includes configuring pins of a system logic of the host system to be compatible with the I/O device of the I/O card, and configuring pins of an I/O device on the I/O card to in turn configure the pins of the I/O card with a configuration setting compatible with the host system.