Invention Grant
- Patent Title: Process for preparing benzimidazole compounds
- Patent Title (中): 制备苯并咪唑化合物的方法
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Application No.: US11993745Application Date: 2006-06-21
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Publication No.: US08039637B2Publication Date: 2011-10-18
- Inventor: John DeMattei , Sagar Shakya , Anthony D. Piscopio , Bruno P. Hache , Matthew Charles Evans , James Gair Ford , Simon Mark Pointon , Koen Peeters , Timothy John Lilley , John Leonard
- Applicant: John DeMattei , Sagar Shakya , Anthony D. Piscopio , Bruno P. Hache , Matthew Charles Evans , James Gair Ford , Simon Mark Pointon , Koen Peeters , Timothy John Lilley , John Leonard
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agent John R. Moore, Esq.; Sarah S. Mastous, Agent
- International Application: PCT/US2006/024084 WO 20060621
- International Announcement: WO2007/002157 WO 20070104
- Main IPC: C07D235/06
- IPC: C07D235/06 ; C07D235/08 ; C07D403/04 ; C07D403/06
Abstract:
Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-1 and their synthetic intermediates: wherein Z, X1, X2, X5, R2 and R10 are as defined herein. Compounds of Formula Ia-1 and their synthetic intermediates can be used to prepare heterocyclic derivatives such as benzimidazole derivatives.
Public/Granted literature
- US20100145065A1 PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS Public/Granted day:2010-06-10
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