A Multiple In Multiple Out (MIMO) communication system comprises an air interface scheduler for allocating air interface resource to a plurality of user equipments transmitting to a MIMO receiver. A vector processor of the scheduler determines a receive equalizer vector for the MIMO receiver for each of a plurality of user equipments in response to a channel matrix for the user equipment. The vector processor may specifically apply singular value decomposition to the channel matrix to determine the receive equalizer vector. An orthogonality processor then determines orthogonality measures between receive equalizer vectors for different sets of user equipments. A selection processor selects a set of user equipments to be allocated a shared MIMO air interface resource in response to the orthogonality measures. By scheduling in response to orthogonality of receiver operations, a reduced interference and/or reduced receiver complexity can be achieved.