A clamping device for therapeutic applications can comprise an extended handle, a powered linear actuator mounted to the extended handle, and a C-shaped clamp attached to the extended handle and including a stationary jaw. The actuator can be configured to provide reversible axial movement of a movable member. The clamping device can further include a pair of applicators attached to the stationary jaw and to the movable member, respectively. The applicators can be made of an hypoallergenic material configured not to cause an adverse reaction when applied to a human skin. The clamping device can further include a switch configured to control the linear actuator. The linear actuator can be configured, responsive to switching the switch, to axially move the second applicator towards and away from the first applicator, thus applying pressure to a targeted body area.