An object of the present invention is to provide an automatic analysis method and an automatic analyzer which are suitable for improving throughput by changing reagents during analysis without placing a load on an operator, and without stopping the analysis. There is provided an automatic analysis method comprising the steps of: while moving a reagent transfer mechanism with respect to a reagent pipettor, dispensing a reagent placed in the reagent transfer mechanism by use of the reagent pipettor to cause a sample to react with the dispensed reagent; and measuring the reacted sample so as to analyze specified analysis items of the sample. A reagent is transferred from a reagent storage unit to a reagent changing mechanism. Then, the reagent changing mechanism is moved in synchronization with the reagent transfer mechanism so that reagents are changed during the synchronization.