Invention Grant
- Patent Title: Process for preparing pharmaceutical compound and intermediates thereof
- Patent Title (中): 制备药物化合物的方法及其中间体
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Application No.: US12138488Application Date: 2008-06-13
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Publication No.: US08048853B2Publication Date: 2011-11-01
- Inventor: Audun Heggelund , Ole Heine Kvernenes , Vidar Bjørnstad
- Applicant: Audun Heggelund , Ole Heine Kvernenes , Vidar Bjørnstad
- Applicant Address: DK Copenhagen
- Assignee: Xellia Pharmaceuticals APS
- Current Assignee: Xellia Pharmaceuticals APS
- Current Assignee Address: DK Copenhagen
- Agent Christian D. Abel
- Main IPC: A61K38/12
- IPC: A61K38/12 ; C07K1/00

Abstract:
The present invention relates to novel intermediates of formula VII, or an acid addition salt or a solvate thereof, wherein R1 is —(CO)NH2, —CH2NH2 or —CN; R2=R3=H or R2 and R3 together form a cyclic boronate or borate ester; X is a helping group selected from the group consisting of i) a five or six membered heterocyclic aromatic ring and derivatives thereof comprising at least one N-atom being a part of an imine-group, wherein said N-atom forms the point of connection to the cyclohexapeptide ring, and ii) tetrazolyl and derivatives thereof for which a nitrogen atom forms the point of connection to the cyclohexapeptide ring, and a process for the preparation of caspofungin utilizing said intermediates.
Public/Granted literature
- US20090312541A1 Process for preparing pharmaceutical compound and intermediates thereof Public/Granted day:2009-12-17
Information query
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