Invention Grant
US08048881B2 Pyrimidine derivatives and their use as P2Y12 receptor antagonists
有权
嘧啶衍生物及其作为P2Y12受体拮抗剂的用途
- Patent Title: Pyrimidine derivatives and their use as P2Y12 receptor antagonists
- Patent Title (中): 嘧啶衍生物及其作为P2Y12受体拮抗剂的用途
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Application No.: US11912545Application Date: 2006-04-27
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Publication No.: US08048881B2Publication Date: 2011-11-01
- Inventor: Eva Caroff , Heinz Fretz , Kurt Hilpert , Olivier Houille , Francis Hubler , Emmanuel Meyer
- Applicant: Eva Caroff , Heinz Fretz , Kurt Hilpert , Olivier Houille , Francis Hubler , Emmanuel Meyer
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates LLC
- Priority: WOPCT/EP2005/004578 20050428; WOPCT/IB2005/053711 20051110
- International Application: PCT/IB2006/051318 WO 20060427
- International Announcement: WO2006/114774 WO 20061102
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/505
Abstract:
The invention relates to 4-aminocarbonyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention and/or treatment of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
Public/Granted literature
- US20080194576A1 Pyrimidine Derivatives and Their Use as P2Y12 Receptor Antagonists Public/Granted day:2008-08-14
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