Invention Grant
- Patent Title: Methods for isolation of triptolide compounds from Tripterygium wilfordii
- Patent Title (中): 雷公藤雷公藤红素分离方法
-
Application No.: US10588883Application Date: 2005-02-07
-
Publication No.: US08048914B2Publication Date: 2011-11-01
- Inventor: Jinhua An , Rensheng Xu , John H. Musser
- Applicant: Jinhua An , Rensheng Xu , John H. Musser
- Applicant Address: US CA Redwood City
- Assignee: Pharmagenesis, Inc.
- Current Assignee: Pharmagenesis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: King & Spalding LLP
- Agent Susan J. Myers Fitch; Peter J. Dehlinger
- International Application: PCT/US2005/003888 WO 20050207
- International Announcement: WO2005/077008 WO 20050825
- Main IPC: A61K31/34
- IPC: A61K31/34

Abstract:
Methods for extraction, isolation, and purification of therapeutically useful compounds from Tripterygium wilfordii are described. Extraction steps employing aqueous base and a hydrocarbon solvent, respectively, are found to increase the efficiency of the process and reduce the amount of material that must be removed by chromatography.
Public/Granted literature
- US20070282114A1 Methods For Isolation Of Triptolide Compounds From Tripterygium WilfordII Public/Granted day:2007-12-06
Information query