Invention Grant
US08048993B2 Heparanase specific molecular probes and their use in research and medical applications
失效
肝素酶特异性分子探针及其在研究和医学应用中的应用
- Patent Title: Heparanase specific molecular probes and their use in research and medical applications
- Patent Title (中): 肝素酶特异性分子探针及其在研究和医学应用中的应用
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Application No.: US12003999Application Date: 2008-01-04
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Publication No.: US08048993B2Publication Date: 2011-11-01
- Inventor: Iris Pecker , Israel Vlodavsky , Yael Friedmann , Tuvia Peretz
- Applicant: Iris Pecker , Israel Vlodavsky , Yael Friedmann , Tuvia Peretz
- Applicant Address: IL Rehovot IL Jerusalem
- Assignee: InSight Biopharmaceuticals Ltd.,Hadasit Medical Research Services and Development Ltd.
- Current Assignee: InSight Biopharmaceuticals Ltd.,Hadasit Medical Research Services and Development Ltd.
- Current Assignee Address: IL Rehovot IL Jerusalem
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/40 ; C07K14/00
Abstract:
According to the present invention there is provided an antibody that specifically binds an epitope of a heparanase protein, the heparanase protein including an amino acid sequence as set forth in SEQ ID NO:2, provided that phenylalanine replaces tyrosine at position 246. The present invention also provides an antibody elicited by an epitope of a heparanase protein, the heparanase protein including an amino acid sequence as set forth in SEQ ID NO:2, provided that phenylalanine replaces tyrosine at position 246.
Public/Granted literature
- US20090099341A1 Heparanase specific molecular probes and their use in research and medical applications Public/Granted day:2009-04-16
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