Invention Grant
- Patent Title: Mediated cellular delivery of LNA oligonucleotides
- Patent Title (中): 介导LNA寡核苷酸的细胞递送
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Application No.: US12523678Application Date: 2008-01-18
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Publication No.: US08048998B2Publication Date: 2011-11-01
- Inventor: Soeren Vestergaard Rasmussen , Torsten Bryld , Soeren Moeller
- Applicant: Soeren Vestergaard Rasmussen , Torsten Bryld , Soeren Moeller
- Applicant Address: DK Vedbaek
- Assignee: Exiqon A/S
- Current Assignee: Exiqon A/S
- Current Assignee Address: DK Vedbaek
- Agency: Clark & Elbing LLP
- Agent Kristina Bieker-Brady
- Priority: DK200700087 20070119
- International Application: PCT/DK2008/000019 WO 20080118
- International Announcement: WO2008/086807 WO 20080724
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K31/70
Abstract:
The present invention relates to novel modified oligomeric compounds and to methods of making and using such compounds. The invention further relates to methods of enhancing the cellular uptake of oligomeric compounds comprising conjugating a metal chelator to those.
Public/Granted literature
- US20100035968A1 MEDIATED CELLULAR DELIVERY OF LNA OLIGONUCLEOTIDES Public/Granted day:2010-02-11
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