Invention Grant
- Patent Title: Aminoquinoline derivatives, preparation method thereof and pharmaceutical composition comprising the same
- Patent Title (中): 氨基喹啉衍生物,其制备方法和包含其的药物组合物
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Application No.: US12468292Application Date: 2009-05-19
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Publication No.: US08049014B2Publication Date: 2011-11-01
- Inventor: Kyung-Ho Yoo , Dong-Jin Kim , Bong-Soo Nam , Chang-Hyun Oh , So-Ha Lee , Seung-Joo Cho , Tae-Bo Sim , Jung-Mi Hah
- Applicant: Kyung-Ho Yoo , Dong-Jin Kim , Bong-Soo Nam , Chang-Hyun Oh , So-Ha Lee , Seung-Joo Cho , Tae-Bo Sim , Jung-Mi Hah
- Applicant Address: KR
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR
- Agency: Ostrolenk Faber LLP
- Priority: KR10-2009-0025560 20090325
- Main IPC: C07D215/38
- IPC: C07D215/38 ; A61K31/04

Abstract:
Provided are a novel aminoquinoline compound represented by Formula 1 or a pharmaceutically acceptable salt thereof, preparation method thereof, and a pharmaceutical composition for preventing or treating cutaneous cancer, comprising the aminoquinoline compound or pharmaceutically acceptable salt thereof. Since the compound of Formula 1 exhibits excellent anti-proliferative effect on melanoma tumor cells, it is useful for preventing or treating cutaneous cancer. wherein R1, R2, and R3 are defined in the specification.
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