Invention Grant
US08049016B2 Thiazole derivatives which inhibit stearoyl-CoA desaturase enzymes
有权
抑制硬脂酰辅酶A去饱和酶的噻唑衍生物
- Patent Title: Thiazole derivatives which inhibit stearoyl-CoA desaturase enzymes
- Patent Title (中): 抑制硬脂酰辅酶A去饱和酶的噻唑衍生物
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Application No.: US12378997Application Date: 2009-02-20
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Publication No.: US08049016B2Publication Date: 2011-11-01
- Inventor: Sultan Chowdhury , Natalie Dales , Julia Fonarev , Jianmin Fu , Duanjie Hou , Qi Jia , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Shaoyi Sun , Zaihui Zhang
- Applicant: Sultan Chowdhury , Natalie Dales , Julia Fonarev , Jianmin Fu , Duanjie Hou , Qi Jia , Vishnumurthy Kodumuru , Natalia Pokrovskaia , Shaoyi Sun , Zaihui Zhang
- Applicant Address: CH Basel CA Burnaby
- Assignee: Novartis AG,Xenon Pharmaceuticals Inc
- Current Assignee: Novartis AG,Xenon Pharmaceuticals Inc
- Current Assignee Address: CH Basel CA Burnaby
- Agent Theresa Devlin
- Main IPC: C07D277/20
- IPC: C07D277/20 ; C07D417/14 ; C07D401/04 ; A61K31/501 ; A61K31/4965 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; A61K31/4436 ; A61K31/427
Abstract:
The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed.
Public/Granted literature
- US20090264444A1 Organic compounds Public/Granted day:2009-10-22
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