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US08051878B2 Magnetic valves for performing multi-dimensional assays using one microfluidic chip 失效
用于使用一个微流控芯片进行多维测定的磁阀

Magnetic valves for performing multi-dimensional assays using one microfluidic chip
Abstract:
An apparatus for performing multi-dimensional assays using a microfluidic chip is presented. The apparatus comprises of two crossing series of micro-channels on the microfluidic chip. The apparatus further comprises of a plurality of magnetic valves placed at the crossings and a guiding magnet. When an operator places the guiding magnet in a vicinity of the chip, the guiding magnet produces a proximal magnetic field gradient at a location of each of the plurality of magnetic valves. At the first micro-channel crossing, a magnetic valve controls fluid flow in the first micro-channel, and another magnetic valve controls fluid flow in the second micro-channel at the first micro-channel crossing. Each magnetic valve comprises a magnetic bead and a cavity on the chip next to a corresponding micro-channel section.
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