Invention Grant
- Patent Title: Interferon-β mutants with increased anti-proliferative activity
- Patent Title (中): 干扰素 突变体具有增加的抗增殖活性
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Application No.: US12082365Application Date: 2008-04-09
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Publication No.: US08052964B2Publication Date: 2011-11-08
- Inventor: Rene Gantier , Manuel Vega , Lila Drittanti , Thierry Guyon
- Applicant: Rene Gantier , Manuel Vega , Lila Drittanti , Thierry Guyon
- Applicant Address: KR Seoul
- Assignee: Hanall Biopharma Co., Ltd.
- Current Assignee: Hanall Biopharma Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Sughrue Mion, PLLC
- Main IPC: A61K38/21
- IPC: A61K38/21 ; A01N25/34 ; C07K14/56
Abstract:
Protease resistant modified interferon-beta polypeptides, pharmaceutical compositions and methods of treatment by administering the compositions are provided. The modified interferon-beta polypeptides are orally available; hence pharmaceutical compositions formulated for oral administration also are provided.
Public/Granted literature
- US20090123974A1 Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules Public/Granted day:2009-05-14
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