Invention Grant
US08053200B2 Monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products
有权
单核细胞活化测试能更好地检测医疗产品中的非内毒素致热原性污染物
- Patent Title: Monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products
- Patent Title (中): 单核细胞活化测试能更好地检测医疗产品中的非内毒素致热原性污染物
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Application No.: US12767537Application Date: 2010-04-26
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Publication No.: US08053200B2Publication Date: 2011-11-08
- Inventor: Stephen Poole , Mehul Patel
- Applicant: Stephen Poole , Mehul Patel
- Applicant Address: US IL Deerfield CH Glattpark (Opfikon) unknown Blanche Lane, South Mimms, Potters Bar
- Assignee: Baxter International Inc.,Baxter Healthcare S.A.,National Institute for Biological Standards and Control
- Current Assignee: Baxter International Inc.,Baxter Healthcare S.A.,National Institute for Biological Standards and Control
- Current Assignee Address: US IL Deerfield CH Glattpark (Opfikon) unknown Blanche Lane, South Mimms, Potters Bar
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: G01N33/567
- IPC: G01N33/567 ; C12M1/34
Abstract:
An improved monocyte activation test is described that is better able to detect non-endotoxin pyrogens in medical products, in which a sample is incubated with a monocyte-containing reagent in an assay system comprising at least one surface comprising polypropylene. The invention also concerns assay systems for use in these tests that include at least one microtiter well having at least one interior surface comprising polypropylene and having a shape such that monocyte-containing reagent is concentrated in the well to provide greater cell to cell contact. The invention also relates to a diagnostic kit that can be used to test for the presence of non-endotoxin pyrogens in a sample.
Public/Granted literature
- US20100203551A1 MONOCYTE ACTIVATION TEST BETTER ABLE TO DETECT NON-ENDOTOXIN PYROGENIC CONTAMINANTS IN MEDIAL PRODUCTS Public/Granted day:2010-08-12
Information query
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