Invention Grant
- Patent Title: Host cells expressing IL-18 receptors
- Patent Title (中): 表达IL-18受体的宿主细胞
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Application No.: US12716993Application Date: 2010-03-03
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Publication No.: US08053233B2Publication Date: 2011-11-08
- Inventor: John E. Sims , Teresa L. Born
- Applicant: John E. Sims , Teresa L. Born
- Applicant Address: US CA Thousand Oaks
- Assignee: Immunex Corporation
- Current Assignee: Immunex Corporation
- Current Assignee Address: US CA Thousand Oaks
- Agent Thomas J. Wrona
- Main IPC: C12N5/10
- IPC: C12N5/10
Abstract:
A novel polypeptide that functions as an IL-18 receptor is disclosed. The receptor is multimeric and includes at least one AcPL polypeptide, or fragment thereof, and at least one IL-1Rrp1 polypeptide, or fraction thereof. The receptor binds IL-18 and finds use in inhibiting biological activities mediated by IL-18.
Public/Granted literature
- US20100190211A1 IL-18 Receptors Public/Granted day:2010-07-29
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