Invention Grant
- Patent Title: Triazole compounds that modulate Hsp90 activity
- Patent Title (中): 调节Hsp90活性的三唑化合物
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Application No.: US11807327Application Date: 2007-05-25
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Publication No.: US08053456B2Publication Date: 2011-11-08
- Inventor: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- Applicant: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D249/12
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Public/Granted literature
- US20080176840A1 Triazole compounds that modulate Hsp90 activity Public/Granted day:2008-07-24
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