Invention Grant
US08067178B2 Gene expression markers for prediction of patient response to chemotherapy
有权
用于预测患者化疗反应的基因表达标志物
- Patent Title: Gene expression markers for prediction of patient response to chemotherapy
- Patent Title (中): 用于预测患者化疗反应的基因表达标志物
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Application No.: US12404268Application Date: 2009-03-13
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Publication No.: US08067178B2Publication Date: 2011-11-29
- Inventor: Joffre B. Baker , Wayne Cowens , Kim Langone , James Hackett , Drew Watson , Soonmyung Paik
- Applicant: Joffre B. Baker , Wayne Cowens , Kim Langone , James Hackett , Drew Watson , Soonmyung Paik
- Applicant Address: US CA Redwood City US PA Pittsburgh
- Assignee: Genomic Health, Inc.,NSABP Foundation, Inc.
- Current Assignee: Genomic Health, Inc.,NSABP Foundation, Inc.
- Current Assignee Address: US CA Redwood City US PA Pittsburgh
- Agency: Bozicevic, Field & Francis LLP
- Agent Carol L. Francis
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53
Abstract:
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material.
Public/Granted literature
- US20090305277A1 GENE EXPRESSION MARKERS FOR PREDICTION OF PATIENT RESPONSE TO CHEMOTHERAPY Public/Granted day:2009-12-10
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