Invention Grant
- Patent Title: MELKS as modifiers of the Rac pathway and methods of use
- Patent Title (中): MELKS作为Rac途径的修饰剂和使用方法
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Application No.: US10567765Application Date: 2004-08-12
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Publication No.: US08067181B2Publication Date: 2011-11-29
- Inventor: Lisa Kadyk , George Ross Francis , Kim Lickteig , Timothy S. Heuer
- Applicant: Lisa Kadyk , George Ross Francis , Kim Lickteig , Timothy S. Heuer
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2004/026231 WO 20040812
- International Announcement: WO2005/016279 WO 20050224
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MELK are provided.
Public/Granted literature
- US20080293044A1 Melks as Modifiers of the Rac Pathway and Methods of Use Public/Granted day:2008-11-27
Information query
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