Invention Grant
US08067574B2 Nucleic acid agents for downregulating H19, and methods of using same
有权
用于下调H19的核酸试剂及其使用方法
- Patent Title: Nucleic acid agents for downregulating H19, and methods of using same
- Patent Title (中): 用于下调H19的核酸试剂及其使用方法
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Application No.: US12015325Application Date: 2008-01-16
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Publication No.: US08067574B2Publication Date: 2011-11-29
- Inventor: Avraham Hochberg , Imad Matouk
- Applicant: Avraham Hochberg , Imad Matouk
- Applicant Address: IL Jerusalem
- Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
- Current Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
- Current Assignee Address: IL Jerusalem
- Agency: Winston & Strawn LLP
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
Isolated oligonucleotides capable of down-regulating H19 mRNA in cancer cells are disclosed, as well as pharmaceutical compositions that include the oligonucleotides and methods of treatment of cancer using them. Methods of treating cancer comprising administering agents capable of downregulating H19 mRNA in combination with an additional anti-cancer treatment are further disclosed.
Public/Granted literature
- US20090203121A1 NUCLEIC ACID AGENTS FOR DOWNREGULATING H19, AND METHODS OF USING SAME Public/Granted day:2009-08-13
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