Invention Grant
- Patent Title: Histone deacetylase inhibitors and methods of use thereof
- Patent Title (中): 组蛋白脱乙酰酶抑制剂及其使用方法
-
Application No.: US12339492Application Date: 2008-12-19
-
Publication No.: US08067600B2Publication Date: 2011-11-29
- Inventor: Alan P. Kozikowski , Bin Chen
- Applicant: Alan P. Kozikowski , Bin Chen
- Applicant Address: US DC Washington
- Assignee: Georgetown University
- Current Assignee: Georgetown University
- Current Assignee Address: US DC Washington
- Agency: Foley Hoag LLP
- Main IPC: C07D217/12
- IPC: C07D217/12 ; C07D215/14 ; A61K31/47
Abstract:
One aspect of the invention relates to HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided. The invention also provides methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.
Public/Granted literature
- US20090163543A1 Histone Deacetylase Inhibitors and Methods of Use Thereof Public/Granted day:2009-06-25
Information query
