Invention Grant
- Patent Title: PRO224 gene disruptions, and methods related thereto
- Patent Title (中): PRO224基因破坏及其相关方法
-
Application No.: US10583466Application Date: 2004-12-13
-
Publication No.: US08067664B2Publication Date: 2011-11-29
- Inventor: Wenhu Huang
- Applicant: Wenhu Huang
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Arnold & Porter LLP
- Agent Bonny Yeung; James A. Fox
- International Application: PCT/US2004/041721 WO 20041213
- International Announcement: WO2005/058028 WO 20050630
- Main IPC: G01N33/00
- IPC: G01N33/00 ; C12N15/00
Abstract:
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO224, PRO9783, PRO1108, PRO34000, PRO240, PRO943, hu A33, PRO230, PRO178, PRO1199, PRO4333, PRO1336, PRO19598, PRO1083, hu TRPM2 or PRO1801 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
Public/Granted literature
- US20070292438A1 Novel Gene Disruptions, Compositions and Methods Relating Thereto Public/Granted day:2007-12-20
Information query
