A 16-State adaptive NPML detector is provided for a tape drive which addresses weaknesses of a conventional fixed, 8-state EPR4 detector. Rather than having a fixed target channel, the detector is programmable to allow a range of target channels and can support “classical” partial response channels such as PR4 or EPR4 by programming predictor or whitening filter coefficients. In one embodiment, two filter coefficients may be set via XREG inputs or dynamically determined through the use of an LMS algorithm allowing the detector to adapt the predictor coefficients as data is being read. Another embodiment provides a detector for an EPR4 target in which the whitening filter has one coefficient. Components of the detection system include the detector itself, an LMS engine, a coefficient engine and a noise predictive or whitening filter. Coefficients from the LMS engine may be loaded or stored dynamically based upon conditions in the tape drive.