Invention Grant
- Patent Title: Viruses for the treatment of cellular proliferative disorders
- Patent Title (中): 用于治疗细胞增殖性疾病的病毒
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Application No.: US12761534Application Date: 2010-04-16
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Publication No.: US08080241B2Publication Date: 2011-12-20
- Inventor: Matthew C. Coffey , Bradley G. Thompson
- Applicant: Matthew C. Coffey , Bradley G. Thompson
- Applicant Address: CA Calgary, Alberta
- Assignee: Oncolytics Biotech Inc.
- Current Assignee: Oncolytics Biotech Inc.
- Current Assignee Address: CA Calgary, Alberta
- Agency: McKeon Meunier Carlin & Curfman, LLC
- Main IPC: A61K39/285
- IPC: A61K39/285 ; A61K39/395 ; C12N15/00

Abstract:
Methods for treating cell proliferative disorders by administering virus to proliferating cells having an activated Ras-pathway are disclosed. The virus is administered so that it ultimately directly contacts proliferating cells having an activated Ras-pathway. Proliferative disorders include but are not limited to neoplasms. The virus is selected from modified adenovirus, modified HSV, modified vaccinia virus and modified parapoxvirus orf virus. Also disclosed are methods for treating cell proliferative disorders by further administering an immunosuppressive agent.
Public/Granted literature
- US20100203147A1 Viruses for the Treatment of Cellular Proliferative Disorders Public/Granted day:2010-08-12
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