Invention Grant
- Patent Title: Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
- Patent Title (中): 应激蛋白组合物和预防和治疗癌症和传染病的方法
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Application No.: US12127499Application Date: 2008-05-27
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Publication No.: US08080388B2Publication Date: 2011-12-20
- Inventor: John R. Subjeck , Robert A. Henderson , Elizabeth A. Repasky , Latif Kazim , Xiang-Yang Wang , Masoud H. Manjili
- Applicant: John R. Subjeck , Robert A. Henderson , Elizabeth A. Repasky , Latif Kazim , Xiang-Yang Wang , Masoud H. Manjili
- Applicant Address: US NY Buffalo
- Assignee: Health Research, Inc.
- Current Assignee: Health Research, Inc.
- Current Assignee Address: US NY Buffalo
- Agency: canady + Lortz LLP
- Agent Karen S. Canady
- Main IPC: C12N15/09
- IPC: C12N15/09 ; C12N5/07 ; C12N5/09 ; C12N5/10
Abstract:
Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immunogenic polypeptide of the stress protein complex can be associated with a cancer or an infectious disease. Preferred immunogenic polypeptides include gp100, her2/neu ECD-PD, ICD and M. tuberculosis antigens. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious disease.
Public/Granted literature
- US20080293103A1 STRESS PROTEIN COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF CANCER AND INFECTIOUS DISEASE Public/Granted day:2008-11-27
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