Invention Grant
- Patent Title: Alleles of the PRPD1 gene from coryneform bacteria
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Application No.: US13009051Application Date: 2011-01-19
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Publication No.: US08080395B2Publication Date: 2011-12-20
- Inventor: Brigitte Bathe , Caroline Kreutzer , Georg Thierbach
- Applicant: Brigitte Bathe , Caroline Kreutzer , Georg Thierbach
- Applicant Address: DE Duesseldorf
- Assignee: Evonik Degussa GmbH
- Current Assignee: Evonik Degussa GmbH
- Current Assignee Address: DE Duesseldorf
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: DE102006050489 20061026
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12P21/06 ; C12P21/04 ; C12P13/04 ; C12N1/20 ; C12N15/00

Abstract:
An isolated mutant of coryneform bacteria comprising a gene encodes a polypeptide having 2-methylcitrate dehydratase activity, where the polypeptide comprises an amino acid sequence in which one of the proteinogenic amino acids except L-proline is present at position 272 or a corresponding or comparable position. In addition, an isolated polynucleotide encoding a polypeptide having 2-methylcitrate dehydratase enzymic activity, which comprises at position 272 of the amino acid sequence or a corresponding or comparable position a proteinogenic amino acid except L-proline is described. A method for producing a recombinant coryneform bacterium and L-amino acids. A recombinant microorganism, L-Lysine-containing feed additive, and L-Tryptophan-containing feed additive is also described.
Public/Granted literature
- US20110171695A1 ALLELES OF THE PRPD1 GENE FROM CORYNEFORM BACTERIA Public/Granted day:2011-07-14
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