Invention Grant
- Patent Title: Shallow multi-well plastic chip for thermal multiplexing
- Patent Title (中): 浅多芯塑料芯片用于热复用
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Application No.: US12288373Application Date: 2008-10-20
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Publication No.: US08080411B2Publication Date: 2011-12-20
- Inventor: Yubo Miao , Yu Chen , Tit Meng Lim , Chew Kiat Heng
- Applicant: Yubo Miao , Yu Chen , Tit Meng Lim , Chew Kiat Heng
- Applicant Address: SG Singapore SG Singapore
- Assignee: Agency for Science, Technology and Research,National University of Singapore
- Current Assignee: Agency for Science, Technology and Research,National University of Singapore
- Current Assignee Address: SG Singapore SG Singapore
- Agency: Saile Ackerman LLC
- Agent Stephen B. Ackerman
- Main IPC: C12M1/02
- IPC: C12M1/02 ; C12M1/40 ; G01N1/44

Abstract:
Disposable units in current use for performing PCR are limited by their heat block ramping rates and by the thermal diffusion delay time through the plastic wall as well as by the sample itself. This limitation has been overcome by forming a disposable plastic chip using a simple deformation process wherein one or more plastic sheets are caused, through hydrostatic pressure, to conform to the surface of a suitable mold. After a given disposable chip has been filled with liquid samples, it is brought into close contact with an array of heating blocks that seals each sample within its own chamber, allowing each sample to then be heat treated as desired.
Public/Granted literature
- US20090053801A1 Shallow multi-well plastic chip for thermal multiplexing Public/Granted day:2009-02-26
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