Invention Grant
- Patent Title: Compounds for enzyme inhibition
- Patent Title (中): 用于酶抑制的化合物
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Application No.: US12708753Application Date: 2010-02-19
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Publication No.: US08080545B2Publication Date: 2011-12-20
- Inventor: Kevin D. Shenk , Francesco Parlati , Han-Jie Zhou , Catherine Sylvain , Mark S. Smyth , Mark K. Bennett , Guy J. Laidig
- Applicant: Kevin D. Shenk , Francesco Parlati , Han-Jie Zhou , Catherine Sylvain , Mark S. Smyth , Mark K. Bennett , Guy J. Laidig
- Applicant Address: US CA South San Francisco
- Assignee: Onyx Therapeutics, Inc.
- Current Assignee: Onyx Therapeutics, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/5377
- IPC: A61K31/5377
Abstract:
One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.
Public/Granted literature
- US20100144648A1 COMPOUNDS FOR ENZYME INHIBITION Public/Granted day:2010-06-10
Information query
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