Invention Grant
- Patent Title: Tricyclic angiotensin II agonists
- Patent Title (中): 三环血管紧张素II激动剂
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Application No.: US11918240Application Date: 2006-04-12
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Publication No.: US08080571B2Publication Date: 2011-12-20
- Inventor: Mathias Alterman , Anders Hallberg , Xiongyu Wu
- Applicant: Mathias Alterman , Anders Hallberg , Xiongyu Wu
- Applicant Address: SE Gothenburg
- Assignee: Vicore Pharma AB
- Current Assignee: Vicore Pharma AB
- Current Assignee Address: SE Gothenburg
- Agency: Nixon & Vanderhye
- International Application: PCT/GB2006/001319 WO 20060412
- International Announcement: WO2006/109048 WO 20061019
- Main IPC: A61K31/4155
- IPC: A61K31/4155 ; A61K31/4174 ; A61K31/4178 ; A61K31/4192 ; C07D233/54 ; C07D249/06 ; C07D231/10

Abstract:
There is provided compounds of formula I, wherein A, X1, X2, X3, X4, Y1, Y2, Y3, Y4, Z1, Z2, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.
Public/Granted literature
- US20090042931A1 Tricyclic Angiotensin II Agonists Public/Granted day:2009-02-12
Information query
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