A computer program product includes a tangible storage medium readable by a processing circuit and storing instructions for execution by the processing circuit for performing a method. The method includes receiving a message to transmit from the channel subsystem to the control unit. The method also includes determining a first CRC insertion position, and receiving a first CRC calculated over a first block of data in the message. The method additionally includes inserting the first calculated CRC at the first CRC insertion position, and determining a second CRC insertion position. The method further includes receiving a second CRC calculated over a second block of data in the message, and inserting the second calculated CRC at the second CRC insertion position.