Invention Grant
- Patent Title: Regulated apoptosis
- Patent Title (中): 调节凋亡
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Application No.: US12684064Application Date: 2010-01-07
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Publication No.: US08084596B2Publication Date: 2011-12-27
- Inventor: Gerald R. Crabtree , Peter Belshaw , Stuart L. Schreiber , David M. Spencer , Thomas J. Wandless
- Applicant: Gerald R. Crabtree , Peter Belshaw , Stuart L. Schreiber , David M. Spencer , Thomas J. Wandless
- Applicant Address: US CA Stanford US MA Cambridge
- Assignee: The Board of Trustees of the Leland Stanford Junior University,President and Fellows of Harvard College
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University,President and Fellows of Harvard College
- Current Assignee Address: US CA Stanford US MA Cambridge
- Agency: Ropes & Gray LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/63 ; C12N15/85
Abstract:
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
Public/Granted literature
- US20100323420A1 REGULATED APOPTOSIS Public/Granted day:2010-12-23
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