Invention Grant
US08084600B2 Short interfering ribonucleic acid (siRNA) with improved pharmacological properties
有权
短干扰核糖核酸（siRNA）具有改善的药理学性质
- Patent Title: Short interfering ribonucleic acid (siRNA) with improved pharmacological properties
- Patent Title (中): 短干扰核糖核酸（siRNA）具有改善的药理学性质
-
Application No.: US12299396Application Date: 2007-05-02
-
Publication No.: US08084600B2Publication Date: 2011-12-27
- Inventor: Francois Jean-Charles Natt , Eric Billy , Juerg Hunziker , Christian Rene Schnell
- Applicant: Francois Jean-Charles Natt , Eric Billy , Juerg Hunziker , Christian Rene Schnell
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Frank Wu
- Priority: GB0608838.9 20060504
- International Application: PCT/EP2007/003867 WO 20070502
- International Announcement: WO2007/128477 WO 20071115
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/11
Abstract:
Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification.
Public/Granted literature
- US20100015707A1 SHORT INTERFERING RIBONUCLEIC ACID (siRNA) FOR ORAL ADMINISTRATION Public/Granted day:2010-01-21
Information query
