A piston-cylinder unit for installing between a vehicle body and an axle includes a cylinder filled with damping medium, a piston dividing the cylinder into working spaces, and a piston rod. A first damping valve assembly in the piston damps movement of the piston in tension and in compression. A load dependent valve includes a valve body which can be moved axially by pressure in the damping medium, the valve body having axially opposed first and second actuation surfaces. The first actuation surface is exposed to pressure of a first accumulator, which is connected to one of the working spaces, and the second actuation surface is exposed to pressure of a second accumulator.