A portable, self-contained device is described for the topical application of oxygen and the removal of wound exudates to promote the healing of skin wounds. The device includes a wound dressing that incorporates at least one electrochemical cell for generating oxygen. The device can regulate the supply of oxygen to the wound at various concentrations, pressures and dosages and is used to produce a high concentration of oxygen at the wound site. By reversing the polarity of the power source a reduced pressure can be created in a reservoir attached to our device. The reduced pressure in the reservoir draws naturally flowing exudates away from the wound. Alternately, two reverse polarity cells are used to alternately supply oxygen and draw away exudates.