Invention Grant
- Patent Title: PFKB3 inhibitor for the treatment of a proliferative cancer
- Patent Title (中): 用于治疗增殖性癌症的PFKB3抑制剂
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Application No.: US12141751Application Date: 2008-06-18
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Publication No.: US08088385B2Publication Date: 2012-01-03
- Inventor: Jason Chesney , John O. Trent , Sucheta Telang , Brian Clem , Jason Meier
- Applicant: Jason Chesney , John O. Trent , Sucheta Telang , Brian Clem , Jason Meier
- Applicant Address: US KY Louisville
- Assignee: University of Louisville Research Foundation Inc.
- Current Assignee: University of Louisville Research Foundation Inc.
- Current Assignee Address: US KY Louisville
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44 ; A61K39/395
Abstract:
A methods and compounds for inhibiting 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase 3 (PFKFB3) are described. Also described are methods of inhibiting cell proliferation, treating cancer, and screening compounds to determine their ability to inhibit PFKFB3.
Public/Granted literature
- US20090074884A1 FAMILY OF PFKFB3 INHIBITORS WITH ANTI-NEOPLASTIC ACTIVITIES Public/Granted day:2009-03-19
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