Invention Grant
- Patent Title: Pharmaceutical compositions comprising fesoterodine
- Patent Title (中): 包含非索罗定的药物组合物
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Application No.: US12342744Application Date: 2008-12-23
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Publication No.: US08088398B2Publication Date: 2012-01-03
- Inventor: Hans-Jürgen Mika , Christoph Arth , Michael Komenda , Fatima Bicane
- Applicant: Hans-Jürgen Mika , Christoph Arth , Michael Komenda , Fatima Bicane
- Applicant Address: DE Monheim
- Assignee: UCB Pharma GmbH
- Current Assignee: UCB Pharma GmbH
- Current Assignee Address: DE Monheim
- Agency: Kenyon & Kenyon LLP
- Main IPC: A01N37/02
- IPC: A01N37/02 ; A61K31/22 ; A61K9/14

Abstract:
The present application relates to a pharmaceutical granulate comprising Fesoterodine or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable stabilizer, which can be selected from the group consisting of sorbitol, xylitol, polydextrose, isomalt, dextrose, and combinations thereof, and is preferably a sugar alcohol selected from the group consisting of xylitol and sorbitol. The granulate is suitable for incorporation into pharmaceutical compositions comprising a gel matrix formed by at least one type of hydroxypropyl methylcellulose into which the Fesoterodine is embedded and, optionally, further excipients. In certain embodiments, the granulate is formed by a process of wet granulation.
Public/Granted literature
- US20090117159A1 PHARMACEUTICAL COMPOSITIONS COMPRISING FESOTERODINE Public/Granted day:2009-05-07
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