Invention Grant
- Patent Title: Assay for methylation in the GST-Pi gene
- Patent Title (中): 测定GST-Pi基因中的甲基化
-
Application No.: US12259920Application Date: 2008-10-28
-
Publication No.: US08088577B2Publication Date: 2012-01-03
- Inventor: Susan J. Clark , Douglas S. Millar , Peter L. Molloy
- Applicant: Susan J. Clark , Douglas S. Millar , Peter L. Molloy
- Applicant Address: AU Campbell
- Assignee: Commonwealth Scientific and Industrial Research Organisation
- Current Assignee: Commonwealth Scientific and Industrial Research Organisation
- Current Assignee Address: AU Campbell
- Agency: Sughrue Mion, PLLC
- Priority: AUPP3129 19980423
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12Q1/68
Abstract:
A diagnostic or prognostic assay is disclosed for a disease of condition characterized by abnormal methylation of cytosine at side or sites within the glutathione-S-transferase (GST) Pi gene and/or its regulatory flanking sequences (e.g., prostate cancer and liver cancer). The assay comprises: (i) isolating DNA from said subject, and (ii) determining (e.g., by selective PCR amplification) the presence of abnormal methylation of cytosine at a site or sites within the GST-Pi gene and/or its regulatory flanking sequences.
Public/Granted literature
- US20090215056A1 Assay for Methylation in the GST-PI Gene Public/Granted day:2009-08-27
Information query
