Invention Grant
US08088729B2 Anti-viral griffithsin compounds, compositions and methods of use
有权
抗病毒性灰质素化合物，组合物和使用方法
- Patent Title: Anti-viral griffithsin compounds, compositions and methods of use
- Patent Title (中): 抗病毒性灰质素化合物，组合物和使用方法
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Application No.: US12095697Application Date: 2006-12-01
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Publication No.: US08088729B2Publication Date: 2012-01-03
- Inventor: Barry O'Keefe , Toshiyuki Mori , James B. McMahon
- Applicant: Barry O'Keefe , Toshiyuki Mori , James B. McMahon
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2006/045930 WO 20061201
- International Announcement: WO2007/064844 WO 20070607
- Main IPC: A01N37/18
- IPC: A01N37/18 ; A61K38/00 ; A61P31/12 ; C07K1/00
Abstract:
A method of inhibiting a viral infection of a host comprising administering to the host an anti-viral griffithsin polypeptide comprising SEQ ID NO: 3 or a fragment thereof comprising at least eight contiguous amino acids, a nucleic acid encoding the anti-viral polypeptide, or an antibody to the anti-viral polypeptide. A method of inhibiting a virus in a sample comprising contacting the sample with an anti-viral griffithsin polypeptide or antibody thereto also is provided.
Public/Granted literature
- US20100221242A1 ANTI-VIRAL GRIFFITHSIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE Public/Granted day:2010-09-02
Information query
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