Invention Grant
- Patent Title: Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
- Patent Title (中): 包含用于治疗血管发生相关疾病的信号素的组合物及其选择方法
-
Application No.: US12738634Application Date: 2008-10-02
-
Publication No.: US08088735B2Publication Date: 2012-01-03
- Inventor: Gera Neufeld , Boaz Kigel , Ofra Kessler , Asya Varshavsky
- Applicant: Gera Neufeld , Boaz Kigel , Ofra Kessler , Asya Varshavsky
- Applicant Address: IL Haifa
- Assignee: Rappaport Family Institute for Research in the Medical Sciences
- Current Assignee: Rappaport Family Institute for Research in the Medical Sciences
- Current Assignee Address: IL Haifa
- International Application: PCT/IL2008/001307 WO 20081002
- International Announcement: WO2009/050691 WO 20090423
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/17 ; C07K14/435
Abstract:
A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
Public/Granted literature
Information query
IPC分类:
