Invention Grant
- Patent Title: Triamine derivative
- Patent Title (中): 三胺衍生物
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Application No.: US11909802Application Date: 2006-03-31
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Publication No.: US08088796B2Publication Date: 2012-01-03
- Inventor: Akiyoshi Mochizuki , Tsutomu Nagata
- Applicant: Akiyoshi Mochizuki , Tsutomu Nagata
- Applicant Address: JP Tokyo
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2005-100335 20050331
- International Application: PCT/JP2006/306930 WO 20060331
- International Announcement: WO2006/106963 WO 20061012
- Main IPC: A61K31/444
- IPC: A61K31/444 ; C07D419/04

Abstract:
An object of the present invention is to provide a novel compound which has a potent inhibitory effect on FXa and exhibits an excellent antithrombotic effect when orally administered. The present invention provides a compound represented by the following general formula (1): wherein R1 and R2 each independently represent a hydrogen atom, a hydroxy group, an alkyl group or an alkoxy group; Q1 represents a saturated or unsaturated bicyclic or tricyclic fused hydrocarbon group which may be substituted, a saturated or unsaturated bicyclic or tricyclic fused heterocyclic group which may be substituted, or the like; Q2 represents a single bond, a straight-chained or branched alkylene group having 1 to 6 carbon atoms, a straight-chained or branched alkenylene group having 2 to 6 carbon atoms, or the like; R3 and R4 each represent an alkyl group, or the like; m and n each represent an integer from 0 to 3; Q4 represents an aryl group; and T0 and T1 each represent a carbonyl group or the like, and a medicine containing the compound.
Public/Granted literature
- US20090239857A1 TRIAMINE DERIVATIVE Public/Granted day:2009-09-24
Information query
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