Invention Grant
- Patent Title: Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor
- Patent Title (中): 包含钠氢交换抑制剂和血管紧张素转化酶抑制剂的药物组合物
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Application No.: US10910912Application Date: 2004-08-04
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Publication No.: US08088799B2Publication Date: 2012-01-03
- Inventor: Wolfgang Linz , Ursula Schindler
- Applicant: Wolfgang Linz , Ursula Schindler
- Applicant Address: DE Frankfurt am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Agent James W. Bolcsak, Esq.
- Priority: DE10204571 20020204
- Main IPC: A61K31/445
- IPC: A61K31/445 ; A61K31/40 ; A61K31/18 ; A61K31/165
Abstract:
This invention is directed to a pharmaceutical composition comprising the sodium-hydrogen exchanger (NHE) inhibitor cariporide and an angiotensin converting enzyme (ACE) inhibitor which exhibits unexpectedly efficacious properties for preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life, and to methods of preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life comprising administering pharmaceutically effective amounts of the sodium-hydrogen exchange inhibitor cariporide and an ACE inhibitor.
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Information query
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